Do not use eletriptan for a headache that is different from your usual migraines . Instead, check with your doctor.

To relieve your migraine as soon as possible, use eletriptan as soon as the headache pain begins.

You may get additional benefit from eletriptan if you lie down in a quiet, dark room after taking eletriptan.

Ask your doctor ahead of time about any other medicine you may take if eletriptan does not work. After you take the other medicine, check with your doctor as soon as possible.

If you feel much better after a dose of eletriptan, but your headache comes back or gets worse after 2 or more hours, you may use one additional dose of eletriptan. Do not take a second tablet if the first did not help your headache at all. However, use this medicine only as directed by your doctor. Do not use more of it, and do not use it more often than directed.

Dosing

The dose of eletriptan will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of eletriptan. If your dose is different, do not change it unless your doctor tells you to do so.

Follow your doctor's orders for preventing migraine.

• For oral dosage form (tablets):
  • For migraine headaches:
    • Adults 20 milligrams (mg) or 40 mg as a single dose. If the migraine comes back after being relieved, another dose be taken two hours or more after the first dose. Do not take more than 2 doses in any twenty-four-hour period
    • Children Use and dose must be determined by your doctor.

Storage

To store this medicine:

• Keep out of the reach of children.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Store away from heat and direct light.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For eletriptan, the following should be considered:

Allergies Tell your doctor if you have ever had any unusual or allergic reaction to eletriptan. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy Eletriptan has not been studied in pregnant women. However, studies in animals have shown that eletriptan causes birth defects and other problems. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding Eletriptan passes into human breast milk. Caution should be used if you are breast feeding. If you are breast feeding, you should discuss the risks and benefits of this medicine with your doctor.

Children Studies on this medicine have been done only in patients 18 years of age or older, and there is no specific information comparing use of eletriptan in children with use in other age groups.

Older adults Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. However, eletriptan has been shown to remain in the body longer in elderly patients. It has also been shown to increase blood pressure.

Other medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. When you are taking eletriptan, it is especially important that your doctor and pharmacist know if you are taking any of the following:

• CYP3A4 inhibitors (clarithromycin [e.g., Biaxin], itraconazole [e.g., Sporonox], ketoconazole [e.g., Nizoral], nefazodone [e.g., Serzone], nelfinavir [e.g., Viracept], ritonavir [e.g., Norvir], troleandomycin [e.g., Tao]) Do not use eletriptan within 72 hours of taking these medicines.

• 5?hydroxytryptamine agonists (almotriptan [e.g., Axert], frovatriptan [e.g., Frova], naratriptan [e.g., Amerge], rizatriptan [e.g., Maxalt], sumatriptan [e.g., Imitrex], zolmitriptan [e.g., Zomig]) or
• Ergot-containing or ergot-type medicines (bromocriptine [e.g., Parlodel], cabergoline [e.g., Dostinex], dihydroergotamine [e.g., D.H.E. 45, Migranal], ergoloid mesylates [e.g., Hydergine], ergonovine [e.g., Ergotrate], ergotamine [e.g., Bellergal, Cafergot, Wigraine], methylergonovine [e.g., Methergine], methysergide [e.g., Sansert], pergolide [e.g., Permax]) Taking eletriptan within 24 hours of taking these medicines may cause serious heart problems.

• Basilar migraine or
• Cerebrovascular syndrome, such as
• Stroke or
• Transient ischemic attack (TIA) or
• Coronary artery disease, such as
• Angina (chest pain) or
• Decreased blood flow to your heart or
• Heart attack, history of, or
• Other heart conditions or
• Hemiplegic migraine or
• High blood pressure, not treated or
• Liver problems, severe or
• Peripheral vascular disease, such as
• Bowel disease or
• Raynaud's syndrome Eletriptan should not be used if you have any of these conditions.

• Cerebrovascular event Eletriptan should be used with caution in patients who have an increased risk of bleeding in the brain, stroke, or transient ischemic attack (TIA).

• Coronary artery disease, predisposition to Eletriptan and similar medicines may cause serious heart problems, especially if you have a predisposition for heart problems.

• High blood pressure, treated Eletriptan may cause high blood pressure in patients already being treated for high blood pressure.

• Kidney problems Eletriptan may cause increased blood pressure in patients who have kidney problems.

• Liver problems, mild or moderate This could cause higher blood levels of eletriptan.