Dosing

The dose of domperidone will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of domperidone.If your dose is different, do not change it unless your doctor tells you to do so.

The number of tablets of that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking domperidone.

• For oral dosage form (tablets):
  • Treatment of gastrointestinal motility disorders:
    • Adults 10 milligrams (mg) three to four times daily. Some patients may require higher doses up to 20 mg three or four times daily.
  • Nausea and vomiting:
    • Adults 20 milligrams (mg) three to four times daily.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For domperidone the following should be considered:

Allergies Tell your doctor if you have ever had any unusual or allergic reaction to domperidone.

Pregnancy Pregnancy domperidone has not been studied in pregnant women. However, domperidone has not been shown to cause birth defects or other problems in animal studies.

Breast-feeding Breast-feeding Domperidone passes into the breast milk, but it is not known if domperidone will cause unwanted effects in the newborn. It may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Children Children Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of domperidone in children with use in other age groups.

Older adults Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing the use of domperidone in the elderly with use in other age groups.

Other medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your doctor or pharmacist if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially:

• Monoamine oxidase (MAO) inhibitors (furazolidone [e.g., Furoxone], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegilene [e.g., Eldepryl], tranylcypromine [e.g., Parnate])

• Bleeding from the stomach or other problems involving the bowels
• Pituitary (brain) tumor
• Liver disease
• Medicine sensitivity to domperidone