Use this medicine only as directed by your doctor. Do not use more or less of it, and do not use it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.

Dosing

The dose of exemestane will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of exemestane. If your dose is different, do not change it unless your doctor tells you to do so.

• For oral dosage form (tablets)
  • For breast cancer in postmenopausal women:
    • Adults 25 milligrams (mg) once a day after a meal.

Missed dose

If you miss a dose of this medicine, do not take the missed dose at all and do not double the next one. Instead, go back to your regular dosing schedule and check with your doctor.

Storage

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For exemestane, the following should be considered:

Allergies Tell your doctor if you have ever had any unusual or allergic reaction to exemestane. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy Exemestane is meant to be used only by women who have experienced menopause and can no longer become pregnant, however, it is important to tell your doctor if you think you might be pregnant. If this medicine is taken by a pregnant woman for any reason it may cause harm to, and possibly even death of, the fetus.

Breast-feeding It is not known whether exemestane passes into human milk. Studies in animals have shown that exemestane passes into rat milk. Because this medicine may cause serious side effects, breast-feeding is generally not recommended while you are taking it.

Older adults Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of exemestane in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Other medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine including the following:

• Estrogens Exemestane may not work as well

• Kidney disease or
• Liver disease It is not known whether moderate or severe kidney or liver disease may increase the chance of side effects during treatment